Los Algodones, Baja California, is a small Mexican town located on the extreme northeastern tip of the municipality of Mexicali, approximately 16 km (9.9 mi) west of Yuma, Arizona, USA. Its official name is Vicente Guerrero also called Molar City. It reported a population of 5,474 as of the 2010 Mexican census. It also serves as a borough seat of its surrounding area.

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Los Algodones is the northernmost town in Mexico, and at its northeastern tip is the northernmost point in Mexico, and in Latin America. Another interesting geographical distinction is that if someone were to travel in any of the four cardinal directions from anywhere in Algodones (due north, due east, due south, or due west), they would cross a U.S. border.

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Situated near the borders of both southeastern California and southwestern Arizona, Los Algodones has become a popular tourist attraction in recent years due in part to inexpensive shopping and restaurants as well as inexpensive medical care and prescription medicines. The warm, dry climate of the area attracts a number of older tourists from across the United States and Canada who settle during the winter in the nearby towns of Yuma, Arizona and Winterhaven, California. Organized day trips from the Coachella Valley are popular among seniors as well.

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From the U.S. side, Los Algodones is most easily reached via Interstate 8 and south a short distance (3.33 Km / 2.07 mi) along State Route 186/Andrade Road to the international border at Andrade, California.